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3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) : ウィキペディア英語版 | 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+)
In enzymology, a 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+) () is an enzyme that catalyzes the chemical reaction :testosterone + NAD+ androst-4-ene-3,17-dione + NADH + H+ Thus, the two substrates of this enzyme are testosterone and NAD+, whereas its 3 products are androst-4-ene-3,17-dione, NADH, and H+. This enzyme belongs to the family of oxidoreductases, specifically those acting on the CH-OH group of donor with NAD+ or NADP+ as acceptor. The systematic name of this enzyme class is 3alpha(or 17beta)-hydroxysteroid:NAD+ oxidoreductase. Other names in common use include 3alpha,17beta-hydroxy steroid dehydrogenase, 3alpha(17beta)-HSD, and 3alpha(17beta)-hydroxysteroid dehydrogenase (NAD+). This enzyme participates in androgen and estrogen metabolism. ==References==
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